The Register has launched it's annual "Guess the Route" contest, which probably means they've got it all mapped out. Conventional wisdom says the route will head north, where it hasn't been in a few years. That's ok by me, so long as it doesn't go south again anytime soon.
But if I could dictate the route, I'd have it slice right through the heart of Iowa. Something like this (with overnight experience indicated): Onawa (5), Lake View (2), Boone (3), Grinnell (3), Vinton (1), Mount Vernon (1), Maquoketa (3) and Sabula (1).
The actual route won't be announced until the end of January. Until then, your guess is as good as mine.